| Name | 2, 3-ribonucleotide |
| Synonyms | 2,3-nucleotide 2, 3-ribonucleotide |
| Physical and Chemical Properties | Chemical quality This product is brown flake or powder. The synthesis of human nucleic acid and a variety of coenzyme precursors has the functions of enhancing body metabolism and promoting hematopoietic function. |
| Use | Use leukocyte-elevating drug. For leukopenia caused by radiation occupation or tumor patients during radiation or drug therapy. Can also be used for non-specific thrombocytopenia and leukopenia and acute and chronic hepatitis. |
Using brewer's yeast as raw material
Extraction, neutralization and precipitation of brewer's yeast are washed with water for 3 times below 10 ℃, filtered to obtain wet yeast cake, add the same amount of water, stir well, add sodium hydroxide until the solution reaches 1%, stir and extract at about 10 ℃ for 2 hours, obtain the extract, add 6mol/L hydrochloric acid to neutralize to pH7, stand for 1-2 days, filter, adjust pH2.5 with 6mol/L hydrochloric acid, stand, collect precipitates to obtain crude RNA.
Yeast [water, sodium hydroxide] & rarr;[<10 ℃] extract [hydrochloric acid] & rarr;[pH7] neutralization solution [hydrochloric acid] & rarr;[pH2.5]RNA crude product
Refining, degrading and drying crude RNA, adding the same amount of water to dissolve, adding sodium hydroxide solution to adjust the pH5-5.5, heating to 80 ℃, cooling, filtering, adding hydrochloric acid to adjust the pH 2.5 of the filtrate, and filtering to obtain RNA refined products. Make a solution of 3%-3.5%, add sodium hydroxide to 1.2%, degrade at 37-45 ℃ for 16-20h, and dry the degradation solution to obtain 2 ', 3'-nucleotides.
RNA crude products [water, sodium hydroxide, hydrochloric acid] & rarr;[pH5-5.5, 80 ℃, pH2.5]RNA refined products [water, sodium hydroxide] & rarr;[37-45 ℃, 16-20h] Mixed 2,3-Nucleotides.